- Name: Articaine hydrochloride
CAS No.: 23964-57-0
Molecular Weight: 320.84
Synonyms: Articaine HCL;2-Thiophenecarboxylicacid, methyl ester,monohydrochloride (8CI);2-Thiophenecarboxylic acid,monohydrochloride (9CI);Carticain;Carticainechlorhydrate;Carticaine hydrochloride;Septanest;Ubistesine;Ultacain;Ultracain;Ultracaine;
Boiling Point: 440.6 °C at 760 mmHg
Flash Point: 220.3 °C
Appearance: white powder
Articaine is a local anaesthetic that has been approved overseas for several years. Like other amide anaesthetics, articaine blocks nerve conduction when it is infiltrated around a nerve. This action is prolonged by combining the drug with a vasoconstrictor .
The combination of articaine can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.
(1) Articaine is used for pain control. Like other local anesthetic drugs, articaine causes a transient
and completely reversible state of anesthesia (loss of sensation) during (dental) procedures.
(2) In dentistry, articaine is used both for infiltration and block injections, with the block technique
yielding the greatest duration of anesthesia.
(3) In people with hypokalemic sensory overstimulation, lidocaine is not very effective, but articaine