Levobupivacaine Hydrochloride

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  • Levobupivacaine Hydrochloride

CAS: 27262-48-2

MF: C18H29ClN2O

MW: 324.89

Product Categories: Pharmaceutical Raw Materials;Active Pharmaceutical Ingredients

Mol File: 27262-48-2.mol

mp 254 °C (dec.)(lit.)

alpha -12.5 º (c=2, water)

Chemical Properties white crystalline powder



Levobupivacaine (rINN) is a local anaesthetic drug belonging to the amino amide group. It is the S-enantiomer of bupivacaine.

The hydrochloride salt of levobupivacaine, an amide derivative with anesthetic property. Levobupivacaine reversibly binds voltage-gated sodium channels to modulate ionic flux and prevent the initiation andtransmission of nerve impulses (stabilizing neuronal membrane), thereby resulting in analgesia and anesthesia.

In comparison with racemic bupivacaine, levobupivacaine is associated with less vasodilation and has a longer duration of action.



Levobupivacaine is the S-enantiomer of bupivacaine hydrochloride and is chemically described as (S)-1-butyl-2-piperidylformo-2′, 6′-xylidide hydrochloride.

Levobupivacaine is a member of the amino amide class of local anaesthetics. It is indicated for surgical anesthesia and postoperative pain management.

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