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GW0742 CAS:317318-84-6

OEM/ODM
The most important part of ordering Steroid powders is actually receiving your order which means two things; firstly that the package passes customs and secondly that the order arrives without sustaining any damages.
Additionally, we also have an array fordisguise techniques to get packages through Customs of Most Countries . we will not discuss these publicly but rest assured they have a very high success rate. Please email for further details on this. we will send you pictures of package and show you where and how to get your powder in our special package. we usually send packageswithin 1-2days, cuz we need a short time to making disguise package, then it will be 4-8days before you received you package.

Categories: .
  • SARMS Raw Powder 317318 – 84 – 6 GW0742 

GW0742 — Quick Details:

GW0742 — Product Name: GW0742

GW0742 — Synonyms: GW0742;;4-[2-(3-FLUORO-4-TRIFLUOROMETHYL-PHENYL)-4-METHYL-THIAZOL-5-YLMETHYLSULFANYL]-2-METHYL-PHENOXY-ACETIC ACID;4-[[[2-[3-Fluoro-4-(trifluoromethyl)phenyl]-4-methyl-5-thiazolyl]methyl]thio]-2-methylphenoxy]AceticAcid;4-[2-(3-Fluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-ylmethylsulfanyl]- 2-methyl-phenoxy}-acetic acidenoxy);GW 0742X

GW0742 — CAS: 317318-84-6

GW0742 — MF: C21H17F4NO3S2

SARMS Raw Powder GW0742 CAS: 317318-84-6 Light Yellow Solid

GW0742 — MW: 471.49

GW0742 — mp  134.5-135.5 °C

GW0742 — storage temp.  2-8°C

GW0742 — solubility  DMSO: >5 mg/mL

fGW0742 — Form : solid

GW0742 — color : white

GW0742 — Chemical Properties Light Yellow Solid

 

GW0742 — Usage:

Usage A small molecule agonist of the human Peroxisome Proliferator-Activated Recept d (PPAR d). It shows an EC50 of 1.1 nM against PPAR d with 100-fold selectivity over the other human subtypes

Usage A small molecule agonist of the human Peroxisome Proliferator-Activated Recept δ (PPAR δ). It shows an EC50 of 1.1 nM against PPAR δ with

100-fold selectivity over the other human subtypes.

GW0742 (also known as GW610742) is a PPARδ/β agonist that is investigated for drug use by GlaxoSmithKline.

 

GW0742 — Description:

A high throughput screening campaign was conducted to identify small molecules with

the ability to inhibit the interaction between the vitamin D receptor (VDR) and steroid

receptor coactivator 2. These inhibitors represent novel molecular probes to modulate

gene regulation mediated by VDR. The peroxisome proliferator-activated receptor δ (PPARδ) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor

antagonist at concentrations higher than 12.1 µM. The highest antagonist activity for

GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742

behaved as PPAR agonist/antagonist activating transcription at lower concentration

and inhibiting this effect at higher concentrations.

 

Competitive Advantage:

Professional Packing

Professional packing with professional materials, and we will give clients several

packing way to choose after you contact me through my email

 

Quality Assurance

Double check for quality of every batch before delivering to customer;

For appearance, we will take pictures of products in advance. We offer the photos to

you for your approval. Especially for lumpy solid, we will check the appearance after

melting to avoid visible contaminations.

For key parameters, we send samples to qualified third party against manufacturer’s

COA or upon customer’s test method. If there is discrepancy, we will inform you

immediately.

Competitive Price

Our extensive relationship with manufacturers in China, allow us to bring you the

highest quality chemicals, ingredients, and additives at a superior price.

The more you buy the more competitive prices you will get.

In time Delivery:

We promise to deliver each batch of products in time, and with the target that deliver

satisfaction rate arrive to 100%.

Service with heart

We Truly Chemical offer specialized logistic service including export declaration,

customs clearance and every detail during shipment. This makes us able to offer you

one-stop service from the order to the products transported to your hand. Truly Chemical

keeps your order in our heart.

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