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Follistatin 315

OEM/ODM
The most important part of ordering Steroid powders is actually receiving your order which means two things; firstly that the package passes customs and secondly that the order arrives without sustaining any damages.
Additionally, we also have an array fordisguise techniques to get packages through Customs of Most Countries . we will not discuss these publicly but rest assured they have a very high success rate. Please email for further details on this. we will send you pictures of package and show you where and how to get your powder in our special package. we usually send packageswithin 1-2days, cuz we need a short time to making disguise package, then it will be 4-8days before you received you package.

  • Follistatin 315

Quick Details: 

Product name:Follistatin 315

Other name:Follistatin

N-terminal Sequence:Gly30

Predicted Molecular Mass:34.7 kDa

Molecular Weight:390

Assay:95%

Appearance:White powder

Min order: 10 vials

Delivery ways: TNT,UPS,DHL,EMS,Fedex

Payment ways: T/T,Western Union ,Money Gram and Bitcoin

 

Description:

Follistatin is a secreted glycoprotein that was first identified as a follicle­stimulating hormone inhibiting substance in ovarian follicular fluid.Human Follistatin cDNA encodes a 344 amino acid protein with a 29 aa signal sequence, an N­terminal atypical TGF binding domain, three Follistatin domains that contain EGF ­like and kazal­like motifs, and a highly acidic C­terminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors.

It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH. In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin 315 is a 34.7 kDa protein containing amino acids 30-344 of the FST-344 protein.

 

Applications:

Follistatin 344 is a naturally occurring human peptide and a potent inhibitor of myostatin. Myostatin encourages the degradation of myotubes therefore inhibition of myostatin will ultimately result in increased muscle mass by preventing degradation.Follistatin is being studied for its role in regulation of muscle growth, as an antagonist to myostatin.

Either by genetic elimination or by increasing the amount of follistatin, resulted in greatly increased muscle mass.In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength.A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy in animal models.

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