dapoxetine

Dapoxetine CAS: 119356-77-3

OEM/ODM
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Quick Details:

  • Dapoxetine

CAS: 119356-77-3
Formula: C21H23NO
MW: 305.4134
Density: 1.081g / cm3
Boiling point: 454.4 ° C at 760 mmHg
Flash Point: 132.6 ° C
Vapor Pressure: 1.91E-08mmHg at 25 ° C

Assay:99.61%

Appearance:White crystalline powder

Applications:

Dapoxetine Treat male premature ejaculation and erectile dysfunction.
 Because lack of specific approval treatment for PE in the US and some othercountries, other SSRIs such as fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram have been used as off label drugs to treat PE. Waldinger’s meta analysisshows that the use of these conventional antidepressants increasing IELT from two to ninefold above base line in comparison of three to eightfold when dapoxetine is used.  However, these SSRIs must be taken daily in order to achieve meaningful efficacy,  and the long half-life increases the risk of the drug accumulation and as aconsequence increased of adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug’s accumulation in the body, and therefore reducing side effects.

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