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AICAR 220-097-5

OEM/ODM
The most important part of ordering Steroid powders is actually receiving your order which means two things; firstly that the package passes customs and secondly that the order arrives without sustaining any damages.
Additionally, we also have an array fordisguise techniques to get packages through Customs of Most Countries . we will not discuss these publicly but rest assured they have a very high success rate. Please email for further details on this. we will send you pictures of package and show you where and how to get your powder in our special package. we usually send packageswithin 1-2days, cuz we need a short time to making disguise package, then it will be 4-8days before you received you package.

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  • AICAR 220-097-5 

Alias:AICAR; AICA-RIBOSIDE; AMPK; Z-RIBOSIDE
CAS:2627-69-2
EINECS:220-097-5
Molecular Formula:C9H14N4O5
Molecular Weight:258.23
Apperance: White or off-white powder.

 

Acadesine/AICAR Powder Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).

Description: 

AICAR is a peptide whose technical name is 5-Aminoimidazole-4-carboxamide ribonucleotide.  It can also be known as AICA ribonucleotide, ZMP, or Acadesine.  It is an intermediate contained in the generation of inosine monophosphate.  It primarily functions as an AMP-activated protein kinase agonist, meaning that it has the ability to promote the operation of nutrient stores for energy production.  It has a molecular mass of 338.211, and it has a molecular formula of C9H15N4O8P.

AICAR is an adenosine analog that selectively activates AMP-activated protein kinase (AMPK). AMPK regulates lipid and glucose metabolism to maintain cellular energy homeostasis (Hardie and Carling).

AICAR can play a hand in boosting these processes because it contains the ability to penetrate cardiac cells and block the production of enzymes tied to regulating glucose intake and energy expulsion.  With these regulatory enzymes inhibited, the affected cells can in turn boost the amount of glucose that can be received, and it can also increase its level of energy conversion.  Additionally, the peptide’s presence has been determined to aid in lowering programmed cell death, a process that is also known as apoptosis.

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